How to perform medium exchange in Akura 96

3D human in vitro cell models are gaining increased importance in the drug discovery and development cycle of the pharmaceutical industry as they mimic the human in vivo responses of newly developed substances more precisely than 2D models. They can help to bridge the gap between the traditional 2D in vitro models and whole-animal systems as the traditional models do not effectively recapitulate the more complex signalling and cellular interactions found in vivo. Spheroids are scaffold-free 3D cell culture models that are aggregated from one or more organ-specific cell types.