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FORTNIGHTLY UPDATE / 19 Nov 2024
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Hello!
The Clinical Trials in Alzheimer’s Disease congress took place last week in Madrid, with BioArctic co-founder, Lars Lannfelt, receiving the Lifetime Achievement Award in Alzheimer’s Disease Therapeutic Research. His research on the amyloid beta protein eventually led to the development of lecanemab. In a statement, he said: "This field of research is in the midst of a paradigm shift driven by the development of treatments such as lecanemab, which has demonstrated meaningful benefits to patients in the large phase III trial Clarity AD using gold standard endpoints. Coupled with the introduction of new diagnostic methods, I am convinced that within a number of years, we will not only be able to slow the progression of the disease, but eventually also stop the disease process entirely." Incidentally, when I first started out in my career as a science writer, one of my first stories focused on amyloid plaques and Alzheimer’s so it’s incredible to see the progress that has been made since then.
As part of a special feature focused on the future of the biopharma industry, The Medicine Maker has been asking people for their views on the future of medicine. Alzheimer’s disease is a topic that has been mentioned frequently in submissions. You can read the opinions here. Steph Vine, Editor of The Medicine Maker
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Essential Reading
US Media Hype Vaccine Ban In an interview with NBC News, Donald Trump reportedly said that Robert F Kennedy, Jr. – well known for his vaccine skepticism – would play a “big role in the administration” if Trump were to win the US presidential election this week. Media headlines are claiming that Trump has refused to rule out bans on vaccines.
Abbvie’s Neuroscience and Cancer Focus Collaborations, license agreements, and an acquisition; it’s been a busy few weeks for Abbvie. The company has announced a discovery, co-development, and license agreement with Gedeon Richter to advance novel targets for neuropsychiatric conditions, and will also be strengthening its neuroscience pipeline with the acquisition of Aliada Therapeutics for $1.4 billion. Cancer is also a focus of Abbvie. The company has agreed a cancer collaboration with EvolveImmune Therapeutics involving multispecific biologics. |
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In Other News
Phase III trial of Moderna’s norovirus mRNA vaccine launched in UK; aims to recruit 2,500 participants between now and early 2025. Fujifilm Diosynth completes first phase of expansion at Hillerød site, adding 6 bioreactors; second phase will add 8 more bioreactors and two downstream processing streams. WHO names 17 pathogens as priority targets for new vaccine development including HIV-1, hepatitis C, group A streptococcus, klebsiella pneumoniae, among others. Transgene and ProBioGen agree license deal for ProBioGen’s AGE1.CR.pIX suspension cell line. Jason Bock of CTMC highlights the need for new manufacturing solutions and supply chain improvements in cell therapy.Neogap Therapeutics agrees collaboration with NorthX Biologics for cancer cell therapy manufacturing strategies. Nxera Pharma and Antiverse to design GPCR-targeted antibody therapeutics using GenAI. |
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